Phasing and Imputing SNPs with Julia

• Tech Stack: Julia, MendelImpute.jl, Beagle, Bash Language, Python

• Members: Me, André Silva Maróstica, Msc. Ágnis Iohana Grefenhagen, Msc. Raphael Amemiya

Built a Hidden-Markov chain model to phase and impute the missing data from DNA, which imputed the SNPs from Illumina to thermoFisher.

The Illumina SNPs sequencing chip have 90 thousand bases that interfere on the poligenic risk score, from the MendelImpute.jl application after using parental genetic data from the 1000 genomes, we phase and impute the missing SNPs from the chips.